Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor int...
Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Protein aggregates associated with neurodegenerative diseases have the ability to transmit to unaffected cells, thereby templating their own aberrant conformation onto soluble homotypic proteins. Proteopathic seeds can be released into the extracellular space, secreted in association with extracellular vesicles (EV) or exchanged by direct cell-to-c...
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Full title
Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions
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TN_cdi_doaj_primary_oai_doaj_org_article_3c987601848e42e7821270559f3b20a9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c987601848e42e7821270559f3b20a9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25855-2
