Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer
Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
ABCB1
encodes Multidrug Resistance protein (MDR1), an ATP-binding cassette member involved in the cellular efflux of chemotherapeutic drugs. Here we report that ovarian and breast samples from chemotherapy treated patients are positive for multiple transcriptional fusions involving
ABCB1
, placing it under the control of a strong promoter...
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Full title
Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_3d60dcd89a874c7d9dd75f1ea6c6ed3b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d60dcd89a874c7d9dd75f1ea6c6ed3b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09312-9
