UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendriti...
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
About this item
Full title
Author / Creator
Maschalidi, Sophia , Nunes-Hasler, Paula , Nascimento, Clarissa R , Sallent, Ignacio , Lannoy, Valérie , Garfa-Traore, Meriem , Cagnard, Nicolas , Sepulveda, Fernando E. , Vargas, Pablo , Lennon-Duménil, Ana-Maria , van Endert, Peter , Capiod, Thierry , Demaurex, Nicolas , Darrasse-Jèze, Guillaume and Manoury, Bénédicte
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Dendritic cells (DC) have the unique ability to present exogenous antigens via the major histocompatibility complex class I pathway to stimulate naive CD8
+
T cells. In DCs with a non-functional mutation in
Unc93b1
(3d mutation), endosomal acidification, phagosomal maturation, antigen degradation, antigen export to the cytosol and the f...
Alternative Titles
Full title
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3df7bd0b89fc4e89876f33ce40769f73
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3df7bd0b89fc4e89876f33ce40769f73
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01601-5
