LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Adult neural stem cells (NSCs) must tightly regulate quiescence and proliferation. Single-cell analysis has suggested a continuum of cell states as NSCs exit quiescence. Here we capture and characterize in vitro primed quiescent NSCs and identify LRIG1 as an important regulator. We show that BMP-4 signaling induces a dormant non-cycling quiescent s...
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Full title
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_3e0ce24ca18642ab920706ba35de6dae
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e0ce24ca18642ab920706ba35de6dae
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22813-w
