Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
About this item
Full title
Author / Creator
Chatterjee, Snehajyoti , Cassel, Raphaelle , Schneider‐Anthony, Anne , Merienne, Karine , Cosquer, Brigitte , Tzeplaeff, Laura , Halder Sinha, Sarmistha , Kumar, Manoj , Chaturbedy, Piyush , Eswaramoorthy, Muthusamy , Le Gras, Stéphanie , Keime, Céline , Bousiges, Olivier , Dutar, Patrick , Petsophonsakul, Petnoi , Rampon, Claire , Cassel, Jean‐Christophe , Buée, Luc , Blum, David , Kundu, Tapas K and Boutillier, Anne‐Laurence
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of tauopathy following treatment with CSP‐TTK21, a small‐molecule activato...
Alternative Titles
Full title
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
Authors, Artists and Contributors
Author / Creator
Cassel, Raphaelle
Schneider‐Anthony, Anne
Merienne, Karine
Cosquer, Brigitte
Tzeplaeff, Laura
Halder Sinha, Sarmistha
Kumar, Manoj
Chaturbedy, Piyush
Eswaramoorthy, Muthusamy
Le Gras, Stéphanie
Keime, Céline
Bousiges, Olivier
Dutar, Patrick
Petsophonsakul, Petnoi
Rampon, Claire
Cassel, Jean‐Christophe
Buée, Luc
Blum, David
Kundu, Tapas K
Boutillier, Anne‐Laurence
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3e3bcfa696b14836b0aa51926f42e2db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3bcfa696b14836b0aa51926f42e2db
Other Identifiers
ISSN
1757-4676,1757-4684
E-ISSN
1757-4684
DOI
10.15252/emmm.201708587
