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ArticlesPeer ReviewedFull Text
Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity
Author / Creator:Wang, Xiao-Lan ; Kooijman, Sander ; Gao, Yuanqing ; Tzeplaeff, Laura ; Cosquer, Brigitte ; Milanova, Irina ; Wolff, Samantha E. C. ; Korpel, Nikita ; Champy, Marie-France ; Petit-Demoulière, Benoit ; Goncalves Da Cruz, Isabelle ; Sorg-Guss, Tania ; Rensen, Patrick C. N. ; Cassel, Jean-Christophe ; Kalsbeek, Andries ; Boutillier, Anne-Laurence ; Yi, Chun-Xia
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-11, Vol.26 (11), p.6336-6349
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ArticlesPeer ReviewedFull Text
Current State and Future Directions in the Therapy of ALS
Author / Creator:Tzeplaeff, Laura ; Wilfling, Sibylle ; Requardt, Maria Viktoria ; Herdick, Meret
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-05, Vol.12 (11), p.1523
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ArticlesPeer ReviewedFull Text
Editorial: Innovative approaches to catalyze preclinical and clinical research on amyotrophic lateral sclerosis (ALS) and related disorders
Author / Creator:Burg, Thibaut ; Tzeplaeff, Laura ; Cassel, Raphaelle ; Lingor, Paul
Publisher:Switzerland: Frontiers Media S.A
Journal title:Frontiers in neuroscience, 2025-03, Vol.19, p.1582539
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ArticlesPeer ReviewedFull Text
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects
Author / Creator:Scekic-Zahirovic, Jelena ; Sanjuan-Ruiz, Inmaculada ; Kan, Vanessa ; Megat, Salim ; De Rossi, Pierre ; Dieterlé, Stéphane ; Cassel, Raphaelle ; Jamet, Marguerite ; Kessler, Pascal ; Wiesner, Diana ; Tzeplaeff, Laura ; Demais, Valérie ; Sahadevan, Sonu ; Hembach, Katharina M. ; Muller, Hans-Peter ; Picchiarelli, Gina ; Mishra, Nibha ; Antonucci, Stefano ; Dirrig-Grosch, Sylvie ; Kassubek, Jan ; Rasche, Volker ; Ludolph, Albert ; Boutillier, Anne-Laurence ; Roselli, Francesco ; Polymenidou, Magdalini ; Lagier-Tourenne, Clotilde ; Liebscher, Sabine ; Dupuis, Luc
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3028-3028, Article 3028
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ArticlesPeer ReviewedFull Text
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
Author / Creator:Caldi Gomes, Lucas ; Hänzelmann, Sonja ; Hausmann, Fabian ; Khatri, Robin ; Oller, Sergio ; Parvaz, Mojan ; Tzeplaeff, Laura ; Pasetto, Laura ; Gebelin, Marie ; Ebbing, Melanie ; Holzapfel, Constantin ; Columbro, Stefano Fabrizio ; Scozzari, Serena ; Knöferle, Johanna ; Cordts, Isabell ; Demleitner, Antonia F. ; Deschauer, Marcus ; Dufke, Claudia ; Sturm, Marc ; Zhou, Qihui ; Zelina, Pavol ; Sudria-Lopez, Emma ; Haack, Tobias B. ; Streb, Sebastian ; Kuzma-Kozakiewicz, Magdalena ; Edbauer, Dieter ; Pasterkamp, R. Jeroen ; Laczko, Endre ; Rehrauer, Hubert ; Schlapbach, Ralph ; Carapito, Christine ; Bonetto, Valentina ; Bonn, Stefan ; Lingor, Paul
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.4893-23, Article 4893
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ArticlesPeer ReviewedFull Text
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
Author / Creator:Chatterjee, Snehajyoti ; Cassel, Raphaelle ; Schneider‐Anthony, Anne ; Merienne, Karine ; Cosquer, Brigitte ; Tzeplaeff, Laura ; Halder Sinha, Sarmistha ; Kumar, Manoj ; Chaturbedy, Piyush ; Eswaramoorthy, Muthusamy ; Le Gras, Stéphanie ; Keime, Céline ; Bousiges, Olivier ; Dutar, Patrick ; Petsophonsakul, Petnoi ; Rampon, Claire ; Cassel, Jean‐Christophe ; Buée, Luc ; Blum, David ; Kundu, Tapas K ; Boutillier, Anne‐Laurence
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2018-11, Vol.10 (11), p.1-n/a
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ArticlesPeer ReviewedFull Text
Unraveling the Heterogeneity of ALS—A Call to Redefine Patient Stratification for Better Outcomes in Clinical Trials
Author / Creator:Tzeplaeff, Laura ; Jürs, Alexandra V. ; Wohnrade, Camilla ; Demleitner, Antonia F.
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-03, Vol.13 (5), p.452
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ArticlesPeer ReviewedFull Text
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription
Author / Creator:Paiva, Isabel ; Cellai, Lucrezia ; Meriaux, Céline ; Poncelet, Lauranne ; Nebie, Ouada ; Saliou, Jean-Michel ; Lacoste, Anne-Sophie ; Papegaey, Anthony ; Drobecq, Hervé ; Le Gras, Stéphanie ; Schneider, Marion ; Malik, Enas M. ; Müller, Christa E. ; Faivre, Emilie ; Carvalho, Kevin ; Gomez-Murcia, Victoria ; Vieau, Didier ; Thiroux, Bryan ; Eddarkaoui, Sabiha ; Lebouvier, Thibaud ; Schueller, Estelle ; Tzeplaeff, Laura ; Grgurina, Iris ; Seguin, Jonathan ; Stauber, Jonathan ; Lopes, Luisa ; Buée, Luc ; Buée-Scherrer, Valérie ; Cunha, Rodrigo ; Ait-Belkacem, Rima ; Sergeant, Nicolas ; Annicotte, Jean-Sébastien ; Boutillier, Anne-Laurence ; Blum, David
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-06, Vol.132 (12), p.1-16
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ArticlesPeer ReviewedFull Text
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects
Author / Creator:Scekic-Zahirovic, Jelena ; Sanjuan-Ruiz, Inmaculada ; Kan, Vanessa ; Megat, Salim ; de Rossi, Pierre ; Dieterlé, Stéphane ; Cassel, Raphaelle ; Jamet, Marguerite ; Kessler, Pascal ; Wiesner, Diana ; Tzeplaeff, Laura ; Demais, Valérie ; Sahadevan, Sonu ; Hembach, Katharina ; Muller, Hans-Peter ; Picchiarelli, Gina ; Mishra, Nibha ; Antonucci, Stefano ; Dirrig-Grosch, Sylvie ; Kassubek, Jan ; Rasche, Volker ; Ludolph, Albert ; Boutillier, Anne-Laurence ; Roselli, Francesco ; Polymenidou, Magdalini ; Lagier-Tourenne, Clotilde ; Liebscher, Sabine ; Dupuis, Luc
Publisher:Nature Publishing Group
Journal title:Nature communications, 2021-12, Vol.12 (1)
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ArticlesPeer ReviewedFull Text
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-de...
Author / Creator:Isabel Paiva ; Lucrezia Cellai ; Céline Meriaux ; Lauranne Poncelet ; Ouada Nebie ; Jean-Michel Saliou ; Anne-Sophie Lacoste ; Anthony Papegaey ; Hervé Drobecq ; Stéphanie Le Gras ; Marion Schneider ; Enas M. Malik ; Christa E. Müller ; Emilie Faivre ; Kevin Carvalho ; Victoria Gomez-Murcia ; Didier Vieau ; Bryan Thiroux ; Sabiha Eddarkaoui ; Thibaud Lebouvier ; Estelle Schueller ; Laura Tzeplaeff ; Iris Grgurina ; Jonathan Seguin ; Jonathan Stauber ; Luisa V. Lopes ; Luc Buée ; Valérie Buée-Scherrer ; Rodrigo A. Cunha ; Rima Ait-Belkacem ; Nicolas Sergeant ; Jean-Sébastien Annicotte ; Anne-Laurence Boutillier ; David Blum
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-06, Vol.132 (12)
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ArticlesFull Text
Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses
Author / Creator:Scekic-Zahirovic, Jelena ; Sanjuan-Ruiz, Inmaculada ; Kan, Vanessa ; Salim Megat ; De Rossi, Pierre ; Dieterle, Stephane ; Cassel, Raphaelle ; Kessler, Pascal ; Wiesner, Diana ; Tzeplaeff, Laura ; Demais, Valerie ; Mueller, Hans-Peter ; Picchiarelli, Gina ; Mishra, Nibha ; Dirrig-Grosch, Sylvie ; Kassubek, Jan ; Rasche, Volker ; Ludolph, Albert C ; Anne-Laurence Boutillier ; Polymenidou, Magdalini ; Lagier-Tourenne, Clotilde ; Liebscher, Sabine ; Dupuis, Luc
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-06
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Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity

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Current State and Future Directions in the Therapy of ALS

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Editorial: Innovative approaches to catalyze preclinical and clinical research on amyotrophic lateral sclerosis (ALS) and related disorders

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Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

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Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target

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Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator

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Unraveling the Heterogeneity of ALS—A Call to Redefine Patient Stratification for Better Outcomes in Clinical Trials

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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription

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Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-de...

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Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses

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