Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of...
Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marrow failure in DC patients is allogeneic hematopoietic stem cell transplantation. However, due to the toxicity associated to this treatment, i...
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Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1
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TN_cdi_doaj_primary_oai_doaj_org_article_3e9b4086c5e84d35a41e8439e2fd5480
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e9b4086c5e84d35a41e8439e2fd5480
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-021-02145-8
