IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
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Author / Creator
Haslund-Gourley, Benjamin S. , Woloszczuk, Kyra , Hou, Jintong , Connors, Jennifer , Cusimano, Gina , Bell, Mathew , Taramangalam, Bhavani , Fourati, Slim , Mege, Nathan , Bernui, Mariana , Altman, Matthew C. , Krammer, Florian , van Bakel, Harm , Maecker, Holden T. , Rouphael, Nadine , Diray-Arce, Joann , Wigdahl, Brian , Kutzler, Michele A. , Cairns, Charles B. , Haddad, Elias K. , Comunale, Mary Ann , IMPACC Network , IMPACC Core Laboratory , IMPACC Clinical Study Team , IMPACC Data Analysis Group , IMPACC Site Investigators , IMPACC Steering Committee and Clinical & Data Coordinating Center (CDCC)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The glycosylation of IgG plays a critical role during human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing cytokine production. However, the role of IgM N-glycosylation has not been studied during human acute viral infection. The analysis of IgM N-glycosylation from healthy controls and...
Alternative Titles
Full title
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
Authors, Artists and Contributors
Author / Creator
Woloszczuk, Kyra
Hou, Jintong
Connors, Jennifer
Cusimano, Gina
Bell, Mathew
Taramangalam, Bhavani
Fourati, Slim
Mege, Nathan
Bernui, Mariana
Altman, Matthew C.
Krammer, Florian
van Bakel, Harm
Maecker, Holden T.
Rouphael, Nadine
Diray-Arce, Joann
Wigdahl, Brian
Kutzler, Michele A.
Cairns, Charles B.
Haddad, Elias K.
Comunale, Mary Ann
IMPACC Network
IMPACC Core Laboratory
IMPACC Clinical Study Team
IMPACC Data Analysis Group
IMPACC Site Investigators
IMPACC Steering Committee
Clinical & Data Coordinating Center (CDCC)
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3ec94a3f579544858deda0f8801d626a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ec94a3f579544858deda0f8801d626a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44211-0