TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion o...
TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Metastatic lung cancer is the leading cause of cancer-associated mortality worldwide, therefore necessitating novel approaches to identify specific genetic drivers for lung cancer progression and metastasis. We recently performed an in vivo gain-of-function genetic screen to identify driver genes of lung cancer metastasis. In the study reported her...
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TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
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TN_cdi_doaj_primary_oai_doaj_org_article_3eec8884c2534e3ab8b673a78e5f82ba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3eec8884c2534e3ab8b673a78e5f82ba
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05013-x
