Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico stu...
Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Despite doxorubicin being commonly used in chemotherapy there still remain significant holes in our knowledge regarding its delivery efficacy and an observed resistance mechanism that is postulated to involve the cell membrane. One possible mechanism is the efflux by protein P-gp, which is found predominantly in cholesterol enriched domains. Thereb...
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Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies
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TN_cdi_doaj_primary_oai_doaj_org_article_3fa980605e2b4fc4a7f70719b932c105
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3fa980605e2b4fc4a7f70719b932c105
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-06445-z
