Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
About this item
Full title
Author / Creator
Wang, Zhiyong , Wu, Victoria H. , Allevato, Michael M. , Gilardi, Mara , He, Yudou , Luis Callejas-Valera, Juan , Vitale-Cross, Lynn , Martin, Daniel , Amornphimoltham, Panomwat , Mcdermott, James , Yung, Bryan S. , Goto, Yusuke , Molinolo, Alfredo A. , Sharabi, Andrew B. , Cohen, Ezra E. W. , Chen, Qianming , Lyons, J. Guy , Alexandrov, Ludmil B. and Gutkind, J. Silvio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited activity (≤20%) in HNSCC, highlighting the need to ide...
Alternative Titles
Full title
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Authors, Artists and Contributors
Author / Creator
Wu, Victoria H.
Allevato, Michael M.
Gilardi, Mara
He, Yudou
Luis Callejas-Valera, Juan
Vitale-Cross, Lynn
Martin, Daniel
Amornphimoltham, Panomwat
Mcdermott, James
Yung, Bryan S.
Goto, Yusuke
Molinolo, Alfredo A.
Sharabi, Andrew B.
Cohen, Ezra E. W.
Chen, Qianming
Lyons, J. Guy
Alexandrov, Ludmil B.
Gutkind, J. Silvio
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3fd2a00b6d274d9893b38fa9d6f2e131
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3fd2a00b6d274d9893b38fa9d6f2e131
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13471-0
