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SquiggleNet: real-time, direct classification of nanopore signals

SquiggleNet: real-time, direct classification of nanopore signals

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_400a7cdd3e9a4dc1a17cb22271f19b24

SquiggleNet: real-time, direct classification of nanopore signals

About this item

Full title

SquiggleNet: real-time, direct classification of nanopore signals

Publisher

England: BioMed Central Ltd

Journal title

Genome Biology, 2021-10, Vol.22 (1), p.298-298, Article 298

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

We present SquiggleNet, the first deep-learning model that can classify nanopore reads directly from their electrical signals. SquiggleNet operates faster than DNA passes through the pore, allowing real-time classification and read ejection. Using 1 s of sequencing data, the classifier achieves significantly higher accuracy than base calling follow...

Alternative Titles

Full title

SquiggleNet: real-time, direct classification of nanopore signals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_400a7cdd3e9a4dc1a17cb22271f19b24

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_400a7cdd3e9a4dc1a17cb22271f19b24

Other Identifiers

ISSN

1474-760X,1474-7596

E-ISSN

1474-760X

DOI

10.1186/s13059-021-02511-y

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