Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect
Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Analyses of longitudinal data with non-linear mixed-effects models (NLMEM) are typically associated with high power, but sometimes at the cost of inflated type I error. Approaches to overcome this problem were published recently, such as model-averaging across drug models (MAD), individual model-averaging (IMA), and combined Likelihood Ratio Test (...
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Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect
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TN_cdi_doaj_primary_oai_doaj_org_article_401da06695ce4fe29d0b7dcf5a35ac26
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_401da06695ce4fe29d0b7dcf5a35ac26
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics15020460
