BMP4 drives primed to naïve transition through PGC-like state
BMP4 drives primed to naïve transition through PGC-like state
About this item
Full title
Author / Creator
Yu, Shengyong , Zhou, Chunhua , He, Jiangping , Yao, Zhaokai , Huang, Xingnan , Rong, Bowen , Zhu, Hong , Wang, Shijie , Chen, Shuyan , Wang, Xialian , Cai, Baomei , Zhao, Guoqing , Chen, Yuhan , Xiao, Lizhan , Liu, He , Qin, Yue , Guo, Jing , Wu, Haokaifeng , Zhang, Zhen , Zhang, Man , Zhao, Xiaoyang , Lan, Fei , Wang, Yixuan , Chen, Jiekai , Cao, Shangtao , Pei, Duanqing and Liu, Jing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Multiple pluripotent states have been described in mouse and human stem cells. Here, we apply single-cell RNA-seq to a newly established BMP4 induced mouse primed to naïve transition (BiPNT) system and show that the reset is not a direct reversal of cell fate but goes through a primordial germ cell-like cells (PGCLCs) state. We first show that epib...
Alternative Titles
Full title
BMP4 drives primed to naïve transition through PGC-like state
Authors, Artists and Contributors
Author / Creator
Zhou, Chunhua
He, Jiangping
Yao, Zhaokai
Huang, Xingnan
Rong, Bowen
Zhu, Hong
Wang, Shijie
Chen, Shuyan
Wang, Xialian
Cai, Baomei
Zhao, Guoqing
Chen, Yuhan
Xiao, Lizhan
Liu, He
Qin, Yue
Guo, Jing
Wu, Haokaifeng
Zhang, Zhen
Zhang, Man
Zhao, Xiaoyang
Lan, Fei
Wang, Yixuan
Chen, Jiekai
Cao, Shangtao
Pei, Duanqing
Liu, Jing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4036486e588644698f0929c8f7056c13
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4036486e588644698f0929c8f7056c13
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30325-4
