The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vascul...
The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells
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Liu, Meichen , Ruan, Xuelei , Liu, Xiaobai , Dong, Weiwei , Wang, Di , Yang, Chunqing , Liu, Libo , Wang, Ping , Zhang, Mengyang and Xue, Yixue
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Vasculogenic mimicry (VM) is an endothelium-independent tumor microcirculation that provides adequate blood supply for tumor growth. The presence of VM greatly hinders the treatment of glioblastoma (GBM) with anti-angiogenic drugs. Therefore, targeting VM formation may be a feasible therapeutic strategy for GBM. The research aimed to evaluate the r...
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Full title
The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_40fce03b383749a2824e393463e17b0f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40fce03b383749a2824e393463e17b0f
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05426-z