Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma
Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma
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Author / Creator
Nomoto, Junko , Hiramoto, Nobuhiro , Kato, Motohiro , Sanada, Masashi , Maeshima, Akiko Miyagi , Taniguchi, Hirokazu , Hosoda, Fumie , Asakura, Yoshitaka , Munakata, Wataru , Sekiguchi, Naohiro , Maruyama, Dai , Watanabe, Takashi , Nakagama, Hitoshi , Takeuchi, Kengo , Tobinai, Kensei , Ogawa, Seishi and Kobayashi, Yukio
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
The TNFAIP3 gene, which encodes a ubiquitin-modifying enzyme (A20) involved in the negative regulation of NF-κB signaling, is frequently inactivated by gene deletions/mutations in a variety of B-cell malignancies. However, the detection of this in primary Hodgkin lymphoma (HL) specimens is hampered by the scarcity of Hodgkin Reed-Sternberg (HR-S) c...
Alternative Titles
Full title
Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_412e73b12a424cefa2ba3f423ea78423
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_412e73b12a424cefa2ba3f423ea78423
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-12-457
