PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Progesterone receptor membrane component 1 (PGRMC1) is a heme-binding protein inducing dimerization with cytochrome P450, which mediates chemoresistance. Increased PGRMC1 expression is found in multiple types of resistant cancers, but the role of PGRMC1 in the ferroptosis of cancer cells remains unrevealed. Therefore, we examined the role of PGRMC1...
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PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_41933309701f4eca826b9aecb9d2a8b1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41933309701f4eca826b9aecb9d2a8b1
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-021-02168-2
