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Inflammasomes as therapeutic targets in human diseases

Inflammasomes as therapeutic targets in human diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41b4364aa6a24f829e403a8d74f75df9

Inflammasomes as therapeutic targets in human diseases

About this item

Full title

Inflammasomes as therapeutic targets in human diseases

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2021-07, Vol.6 (1), p.247-14, Article 247

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammasomes are protein complexes of the innate immune system that initiate inflammation in response to either exogenous pathogens or endogenous danger signals. Inflammasome multiprotein complexes are composed of three parts: a sensor protein, an adaptor, and pro-caspase-1. Activation of the inflammasome leads to the activation of caspase-1, whic...

Alternative Titles

Full title

Inflammasomes as therapeutic targets in human diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_41b4364aa6a24f829e403a8d74f75df9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41b4364aa6a24f829e403a8d74f75df9

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-021-00650-z

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