Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage res...
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response
About this item
Full title
Author / Creator
Dufey, Estefanie , Bravo-San Pedro, José Manuel , Eggers, Cristian , González-Quiroz, Matías , Urra, Hery , Sagredo, Alfredo I. , Sepulveda, Denisse , Pihán, Philippe , Carreras-Sureda, Amado , Hazari, Younis , Sagredo, Eduardo A. , Gutierrez, Daniela , Valls, Cristian , Papaioannou, Alexandra , Acosta-Alvear, Diego , Campos, Gisela , Domingos, Pedro M. , Pedeux, Rémy , Chevet, Eric , Alvarez, Alejandra , Godoy, Patricio , Walter, Peter , Glavic, Alvaro , Kroemer, Guido and Hetz, Claudio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The molecular connections between homeostatic systems that maintain both genome integrity and proteostasis are poorly understood. Here we identify the selective activation of the unfolded protein response transducer IRE1α under genotoxic stress to modulate repair programs and sustain cell survival. DNA damage engages IRE1α signaling in the absence...
Alternative Titles
Full title
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response
Authors, Artists and Contributors
Author / Creator
Bravo-San Pedro, José Manuel
Eggers, Cristian
González-Quiroz, Matías
Urra, Hery
Sagredo, Alfredo I.
Sepulveda, Denisse
Pihán, Philippe
Carreras-Sureda, Amado
Hazari, Younis
Sagredo, Eduardo A.
Gutierrez, Daniela
Valls, Cristian
Papaioannou, Alexandra
Acosta-Alvear, Diego
Campos, Gisela
Domingos, Pedro M.
Pedeux, Rémy
Chevet, Eric
Alvarez, Alejandra
Godoy, Patricio
Walter, Peter
Glavic, Alvaro
Kroemer, Guido
Hetz, Claudio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_41bd77e35d0d4d3fba7541fc5ffc6412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41bd77e35d0d4d3fba7541fc5ffc6412
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15694-y
