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Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in ad...

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in ad...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41de5804a75d4d98bfa174ff84c5c9b5

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma

About this item

Full title

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-12, Vol.11 (1), p.6322-6322, Article 6322

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic osteosarcoma lesions, 11 major cell clusters are identified based on unbiased clustering of gene expression profiles and canonical markers. The transcriptomic properties, reg...

Alternative Titles

Full title

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_41de5804a75d4d98bfa174ff84c5c9b5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41de5804a75d4d98bfa174ff84c5c9b5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-20059-6

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