Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in ad...
Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
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Author / Creator
Zhou, Yan , Yang, Dong , Yang, Qingcheng , Lv, Xiaobin , Huang, Wentao , Zhou, Zhenhua , Wang, Yaling , Zhang, Zhichang , Yuan, Ting , Ding, Xiaomin , Tang, Lina , Zhang, Jianjun , Yin, Junyi , Huang, Yujing , Yu, Wenxi , Wang, Yonggang , Zhou, Chenliang , Su, Yang , He, Aina , Sun, Yuanjue , Shen, Zan , Qian, Binzhi , Meng, Wei , Fei, Jia , Yao, Yang , Pan, Xinghua , Chen, Peizhan and Hu, Haiyan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Osteosarcoma is the most frequent primary bone tumor with poor prognosis. Through RNA-sequencing of 100,987 individual cells from 7 primary, 2 recurrent, and 2 lung metastatic osteosarcoma lesions, 11 major cell clusters are identified based on unbiased clustering of gene expression profiles and canonical markers. The transcriptomic properties, reg...
Alternative Titles
Full title
Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
Authors, Artists and Contributors
Author / Creator
Yang, Dong
Yang, Qingcheng
Lv, Xiaobin
Huang, Wentao
Zhou, Zhenhua
Wang, Yaling
Zhang, Zhichang
Yuan, Ting
Ding, Xiaomin
Tang, Lina
Zhang, Jianjun
Yin, Junyi
Huang, Yujing
Yu, Wenxi
Wang, Yonggang
Zhou, Chenliang
Su, Yang
He, Aina
Sun, Yuanjue
Shen, Zan
Qian, Binzhi
Meng, Wei
Fei, Jia
Yao, Yang
Pan, Xinghua
Chen, Peizhan
Hu, Haiyan
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_41de5804a75d4d98bfa174ff84c5c9b5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41de5804a75d4d98bfa174ff84c5c9b5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20059-6