Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in...
Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Natural killer (NK) cells are lymphocytes with important anti-tumour functions. Cytokine activation of NK cell glycolysis and oxidative phosphorylation (OXPHOS) are essential for robust NK cell responses. However, the mechanisms leading to this metabolic phenotype are unclear. Here we show that the transcription factor cMyc is essential for IL-2/IL...
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Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_428103db6a8c40348a0ae092d9d2a982
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_428103db6a8c40348a0ae092d9d2a982
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04719-2
