Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitox...
Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD
About this item
Full title
Author / Creator
Jaramillo, Sonia , Le Cornet, Lucian , Kratzmann, Markus , Krisam, Johannes , Görner, Martin , Hänel, Mathias , Röllig, Christoph , Wass, Maxi , Scholl, Sebastian , Ringhoffer, Mark , Reichart, Alexander , Steffen, Björn , Kayser, Sabine , Mikesch, Jan-Henrik , Schaefer-Eckart, Kerstin , Schubert, Jörg , Geer, Thomas , Martin, Sonja , Kieser, Meinhard , Sauer, Tim , Kriegsmann, Katharina , Hundemer, Michael , Serve, Hubert , Bornhäuser, Martin , Müller-Tidow, Carsten and Schlenk, Richard F.
Publisher
London: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Background About 50% of older patients with acute myeloid leukemia (AML) fail to attain complete remission (CR) following cytarabine plus anthracycline-based induction therapy. Salvage chemotherapy regimens are based on high-dose cytarabine (HiDAC), which is frequently combined with mitoxantrone (HAM regimen). However, CR rates remain low, with les...
Alternative Titles
Full title
Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD
Authors, Artists and Contributors
Author / Creator
Le Cornet, Lucian
Kratzmann, Markus
Krisam, Johannes
Görner, Martin
Hänel, Mathias
Röllig, Christoph
Wass, Maxi
Scholl, Sebastian
Ringhoffer, Mark
Reichart, Alexander
Steffen, Björn
Kayser, Sabine
Mikesch, Jan-Henrik
Schaefer-Eckart, Kerstin
Schubert, Jörg
Geer, Thomas
Martin, Sonja
Kieser, Meinhard
Sauer, Tim
Kriegsmann, Katharina
Hundemer, Michael
Serve, Hubert
Bornhäuser, Martin
Müller-Tidow, Carsten
Schlenk, Richard F.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_429cfaca4e8047249e5f275e8cfc363c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_429cfaca4e8047249e5f275e8cfc363c
Other Identifiers
ISSN
1745-6215
E-ISSN
1745-6215
DOI
10.1186/s13063-023-07421-x
