DNA-protein cross-link repair: what do we know now?
DNA-protein cross-link repair: what do we know now?
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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When a protein is covalently and irreversibly bound to DNA (i.e., a DNA-protein cross-link [DPC]), it may obstruct any DNA-based transaction, such as transcription and replication. DPC formation is very common in cells, as it can arise from endogenous factors, such as aldehyde produced during cell metabolism, or exogenous sources like ionizing radi...
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DNA-protein cross-link repair: what do we know now?
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TN_cdi_doaj_primary_oai_doaj_org_article_42b28a7be6b74fcbacdaf166a6fc57a1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42b28a7be6b74fcbacdaf166a6fc57a1
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ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-019-0366-z