Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity
Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity
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Author / Creator
Liu, Longqi , Liu, Chuanyu , Quintero, Andrés , Wu, Liang , Yuan, Yue , Wang, Mingyue , Cheng, Mengnan , Leng, Lizhi , Xu, Liqin , Dong, Guoyi , Li, Rui , Liu, Yang , Wei, Xiaoyu , Xu, Jiangshan , Chen, Xiaowei , Lu, Haorong , Chen, Dongsheng , Wang, Quanlei , Zhou, Qing , Lin, Xinxin , Li, Guibo , Liu, Shiping , Wang, Qi , Wang, Hongru , Fink, J. Lynn , Gao, Zhengliang , Liu, Xin , Hou, Yong , Zhu, Shida , Yang, Huanming , Ye, Yunming , Lin, Ge , Chen, Fang , Herrmann, Carl , Eils, Roland , Shang, Zhouchun and Xu, Xun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
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Contents
Integrative analysis of multi-omics layers at single cell level is critical for accurate dissection of cell-to-cell variation within certain cell populations. Here we report scCAT-seq, a technique for simultaneously assaying chromatin accessibility and the transcriptome within the same single cell. We show that the combined single cell signatures e...
Alternative Titles
Full title
Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity
Authors, Artists and Contributors
Author / Creator
Liu, Chuanyu
Quintero, Andrés
Wu, Liang
Yuan, Yue
Wang, Mingyue
Cheng, Mengnan
Leng, Lizhi
Xu, Liqin
Dong, Guoyi
Li, Rui
Liu, Yang
Wei, Xiaoyu
Xu, Jiangshan
Chen, Xiaowei
Lu, Haorong
Chen, Dongsheng
Wang, Quanlei
Zhou, Qing
Lin, Xinxin
Li, Guibo
Liu, Shiping
Wang, Qi
Wang, Hongru
Fink, J. Lynn
Gao, Zhengliang
Liu, Xin
Hou, Yong
Zhu, Shida
Yang, Huanming
Ye, Yunming
Lin, Ge
Chen, Fang
Herrmann, Carl
Eils, Roland
Shang, Zhouchun
Xu, Xun
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_42d28702523949a9a66ecb6233ecbdda
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42d28702523949a9a66ecb6233ecbdda
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08205-7
