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Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4311cc1316a246418b4a4116fe3ac384

Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

About this item

Full title

Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

Publisher

United States: John Wiley & Sons, Inc

Journal title

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2020, Vol.12 (1), p.e12099-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Introduction
Several blood‐based biomarkers are associated with neuronal injury, but their utility in interventional clinical trials is unclear. This study retrospectively evaluated the utility of plasma neurofilament light (NfL) and total tau (t‐tau) in an 18‐month trial in mild Alzheimer's disease (AD).
Methods
Correlation and conditiona...

Alternative Titles

Full title

Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4311cc1316a246418b4a4116fe3ac384

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4311cc1316a246418b4a4116fe3ac384

Other Identifiers

ISSN

2352-8729

E-ISSN

2352-8729

DOI

10.1002/dad2.12099