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Mechanism of U6 snRNA oligouridylation by human TUT1

Mechanism of U6 snRNA oligouridylation by human TUT1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4316472e1bb84ab69a9c78b4b29ca677

Mechanism of U6 snRNA oligouridylation by human TUT1

About this item

Full title

Mechanism of U6 snRNA oligouridylation by human TUT1

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-08, Vol.14 (1), p.4686-4686, Article 4686

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

U6 snRNA is a catalytic RNA responsible for pre-mRNA splicing reactions and undergoes various post-transcriptional modifications during its maturation process. The 3'-oligouridylation of U6 snRNA by the terminal uridylyltransferase, TUT1, provides the Lsm-binding site in U6 snRNA for U4/U6 di-snRNP formation and this ensures pre-mRNA splicing. Here...

Alternative Titles

Full title

Mechanism of U6 snRNA oligouridylation by human TUT1

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4316472e1bb84ab69a9c78b4b29ca677

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4316472e1bb84ab69a9c78b4b29ca677

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-40420-9

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