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Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease o...

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4350d228ebd54f46aff3945119c4aa78

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes

About this item

Full title

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-11, Vol.15 (1), p.9832-12, Article 9832

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sclerostin inhibitors protect against osteoporotic fractures, but their cardiovascular safety remains unclear. We conducted a
cis
-Mendelian randomisation analysis to estimate the causal effect of sclerostin levels on cardiovascular risk factors. We meta-analysed three GWAS of sclerostin levels including 49,568 Europeans and selected 2 SNPs t...

Alternative Titles

Full title

Effect of genetically predicted sclerostin on cardiovascular biomarkers, risk factors, and disease outcomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4350d228ebd54f46aff3945119c4aa78

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4350d228ebd54f46aff3945119c4aa78

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-53623-5

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