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Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating...

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_437af3957800426eb657b070b8e02aa9

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

About this item

Full title

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2018-01, Vol.17 (1), p.19-19, Article 19

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. However, the role of circ-ITCH in bladder cancer (BCa) was not reported. In the present study, we investigated the role of circ-ITCH in BCa.
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Alternative Titles

Full title

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_437af3957800426eb657b070b8e02aa9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_437af3957800426eb657b070b8e02aa9

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-018-0771-7

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