Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating...
Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression
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Author / Creator
Yang, Chengdi , Yuan, Wenbo , Yang, Xiao , Li, Peng , Wang, Jingzi , Han, Jie , Tao, Jun , Li, Pengchao , Yang, Haiwei , Lv, Qiang and Zhang, Wei
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. However, the role of circ-ITCH in bladder cancer (BCa) was not reported. In the present study, we investigated the role of circ-ITCH in BCa.
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Full title
Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression
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TN_cdi_doaj_primary_oai_doaj_org_article_437af3957800426eb657b070b8e02aa9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_437af3957800426eb657b070b8e02aa9
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-018-0771-7