Log in to save to my catalogue

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte bio...

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte bio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_444dcf6d4db4447e90c469502f9a36e5

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

About this item

Full title

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-09, Vol.10 (1), p.4064-14, Article 4064

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Population-based biobanks with genomic and dense phenotype data provide opportunities for generating effective therapeutic hypotheses and understanding the genomic role in disease predisposition. To characterize latent components of genetic associations, we apply truncated singular value decomposition (DeGAs) to matrices of summary statistics deriv...

Alternative Titles

Full title

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_444dcf6d4db4447e90c469502f9a36e5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_444dcf6d4db4447e90c469502f9a36e5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11953-9

How to access this item