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Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derive...

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derive...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44da39f9b2d04b38a658977559d6f81c

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR

About this item

Full title

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-07, Vol.10 (1), p.12332-12332, Article 12332

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It is challenging to secure a cytopathologic diagnosis using minute amounts of tumor fluids and tissue fragments. Hence, we developed a rapid, accurate, low-cost method for detecting tumor cell-derived DNA from limited amounts of specimens and samples with a low tumor cellularity, to detect
KRAS
mutations in pancreatic ductal carcinomas (PDA)...

Alternative Titles

Full title

Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_44da39f9b2d04b38a658977559d6f81c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44da39f9b2d04b38a658977559d6f81c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-69221-6

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