Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
About this item
Full title
Author / Creator
Song, Zhenfeng , Thepsuwan, Pattaraporn , Hur, Woosuk Steve , Torres, Mauricio , Wu, Shuangcheng Alivia , Wei, Xiaoqiong , Tushi, Nusrat Jahan , Wei, Juncheng , Ferraresso, Francesca , Paton, Adrienne W. , Paton, James C. , Zheng, Ze , Zhang, Kezhong , Fang, Deyu , Kastrup, Christian J. , Jaiman, Sunil , Flick, Matthew James and Sun, Shengyi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Impaired secretion of an essential blood coagulation factor fibrinogen leads to hepatic fibrinogen storage disease (HFSD), characterized by the presence of fibrinogen-positive inclusion bodies and hypofibrinogenemia. However, the molecular mechanisms underlying the biogenesis of fibrinogen in the endoplasmic reticulum (ER) remain unexplored. Here w...
Alternative Titles
Full title
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
Authors, Artists and Contributors
Author / Creator
Thepsuwan, Pattaraporn
Hur, Woosuk Steve
Torres, Mauricio
Wu, Shuangcheng Alivia
Wei, Xiaoqiong
Tushi, Nusrat Jahan
Wei, Juncheng
Ferraresso, Francesca
Paton, Adrienne W.
Paton, James C.
Zheng, Ze
Zhang, Kezhong
Fang, Deyu
Kastrup, Christian J.
Jaiman, Sunil
Flick, Matthew James
Sun, Shengyi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_44fed735e7da408086582af319824222
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44fed735e7da408086582af319824222
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53639-x
