Haploflow: strain-resolved de novo assembly of viral genomes
Haploflow: strain-resolved de novo assembly of viral genomes
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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With viral infections, multiple related viral strains are often present due to coinfection or within-host evolution. We describe Haploflow, a deBruijn graph-based assembler for de novo genome assembly of viral strains from mixed sequence samples using a novel flow algorithm. We assess Haploflow across multiple benchmark data sets of increasing comp...
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Haploflow: strain-resolved de novo assembly of viral genomes
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TN_cdi_doaj_primary_oai_doaj_org_article_4514c35b142f47ef960e062abba914bb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4514c35b142f47ef960e062abba914bb
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-021-02426-8