HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanu...
HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy
About this item
Full title
Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
We investigated the interplay between genetics and oral peanut protein exposure in the determination of the immunological response to peanut using the targeted intervention in the LEAP clinical trial. We identified an association between peanut-specific IgG4 and HLA-DQA1*01:02 that was only observed in the presence of sustained oral peanut protein...
Alternative Titles
Full title
HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_456cf36dcc204a449920548713ba281d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_456cf36dcc204a449920548713ba281d
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI152070
