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Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45f8031aa1ce42f587b4ebe1846baae1

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

About this item

Full title

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2017-06, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. Here, we set up two assays to specifically identify the pharmacological properties...

Alternative Titles

Full title

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_45f8031aa1ce42f587b4ebe1846baae1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45f8031aa1ce42f587b4ebe1846baae1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.25233

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