Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. Here, we set up two assays to specifically identify the pharmacological properties...
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Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
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TN_cdi_doaj_primary_oai_doaj_org_article_45f8031aa1ce42f587b4ebe1846baae1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45f8031aa1ce42f587b4ebe1846baae1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.25233