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Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46018f62e17246b7b4a09effe2eea464

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

About this item

Full title

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2021-02, Vol.6 (1), p.94-30, Article 94

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified AA on the inner surface of the cell membrane is hydrolyzed to its free form by phospholipase A2 (PLA2), which is in turn further metabolized by cyclooxygenases (COXs) and lipoxygena...

Alternative Titles

Full title

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_46018f62e17246b7b4a09effe2eea464

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46018f62e17246b7b4a09effe2eea464

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-020-00443-w

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