Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is no...
Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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When activated by the accumulation of unfolded proteins in the endoplasmic reticulum, metazoan IRE1, the most evolutionarily conserved unfolded protein response (UPR) transducer, initiates unconventional splicing of XBP1 mRNA. Unspliced and spliced mRNA are translated to produce pXBP1(U) and pXBP1(S), respectively. pXBP1(S) functions as a potent tr...
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Full title
Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish
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TN_cdi_doaj_primary_oai_doaj_org_article_46bf4fdf763e447b9aef8609169b5b93
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46bf4fdf763e447b9aef8609169b5b93
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.26845
