STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer
STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer
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Author / Creator
Crnčec, Ilija , Modak, Madhura , Gordziel, Claire , Svinka, Jasmin , Scharf, Irene , Moritsch, Stefan , Pathria, Paulina , Schlederer, Michaela , Kenner, Lukas , Timelthaler, Gerald , Müller, Mathias , Strobl, Birgit , Casanova, Emilio , Bayer, Editha , Mohr, Thomas , Stöckl, Johannes , Friedrich, Karlheinz and Eferl, Robert
Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
The interferon‐inducible transcription factor STAT1 is a tumor suppressor in various malignancies. We investigated sex‐specific STAT1 functions in colitis and colitis‐associated colorectal cancer (CRC) using mice with specific STAT1 deletion in intestinal epithelial cells (STAT1∆IEC). Male but not female STAT1∆IEC mice were more resistant to DSS‐in...
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Full title
STAT1 is a sex‐specific tumor suppressor in colitis‐associated colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_470ce83f7ffc4801a6ede8c87a159f05
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_470ce83f7ffc4801a6ede8c87a159f05
Other Identifiers
ISSN
1574-7891,1878-0261
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12178
