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Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_470ec0d9e51d4d6c997ff1c23ab7fac8

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

About this item

Full title

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-05, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Understanding the molecular mechanism of glaucoma and development of neuroprotectants is significantly hindered by the lack of a reliable animal model that accurately recapitulates human glaucoma. Here, we sought to develop a mouse model for the secondary glaucoma that is often observed in humans after silicone oil (SO) blocks the pupil or migrates...

Alternative Titles

Full title

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_470ec0d9e51d4d6c997ff1c23ab7fac8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_470ec0d9e51d4d6c997ff1c23ab7fac8

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.45881

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