Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008
Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008
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England: BioMed Central
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English
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England: BioMed Central
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Drug resistance of B-cell precursor acute lymphoblastic leukemia (BP-ALL) cells is conferred by both intrinsic and extrinsic factors, which could be targeted to promote chemo-sensitization. Our previous studies showed that Galectin-3, a lectin that clusters galactose-modified glycoproteins and that has both an intracellular and extracellular locati...
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Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008
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TN_cdi_doaj_primary_oai_doaj_org_article_473c69e2456944a39311ccf9e58ab06e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_473c69e2456944a39311ccf9e58ab06e
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-018-0721-7