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Targeting STAT3 in Cancer Immunotherapy

Targeting STAT3 in Cancer Immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_47580c2f70e14c39a032e4c19961ebd8

Targeting STAT3 in Cancer Immunotherapy

About this item

Full title

Targeting STAT3 in Cancer Immunotherapy

Publisher

London: BioMed Central Ltd

Journal title

Molecular cancer, 2020-09, Vol.19 (1), p.1-145, Article 145

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune response. STAT3 is broadly hyperactivated both in cancer and non-cancerous cells within the tumor ecosystem and plays important roles in inhibiting the expression of crucial i...

Alternative Titles

Full title

Targeting STAT3 in Cancer Immunotherapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_47580c2f70e14c39a032e4c19961ebd8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_47580c2f70e14c39a032e4c19961ebd8

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-020-01258-7

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