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Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in v...

Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in v...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_489b5d3c620344e6953c3e9f9f7f0134

Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro

About this item

Full title

Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-07, Vol.12 (1), p.12493-12493, Article 12493

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Because rare, but severe adverse effects, i.e. retinal vasculitis or retinal vein occlusion, have been observed after repetitive intravitreal injections of VEGF-A-binding single-chain variable fragment brolucizumab (Beovu), we investigated its possible impact on the barrier formed by immortalized bovine retinal endothelial cells (iBREC) in comparis...

Alternative Titles

Full title

Beovu, but not Lucentis impairs the function of the barrier formed by retinal endothelial cells in vitro

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_489b5d3c620344e6953c3e9f9f7f0134

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_489b5d3c620344e6953c3e9f9f7f0134

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-16770-7

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