Evaluation of moxifloxacin in canine and non‐human primate telemetry assays: Comparison of QTc inter...
Evaluation of moxifloxacin in canine and non‐human primate telemetry assays: Comparison of QTc interval prolongation by timepoint and concentration‐QTc analysis
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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The in vivo correct QT (QTc) assay is used by the pharmaceutical industry to characterize the potential for delayed ventricular repolarization and is a core safety assay mentioned in International Conference on Harmonization (ICH) S7B guideline. The typical telemetry study involves a dose‐response analysis of QTc intervals over time using a crossov...
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Evaluation of moxifloxacin in canine and non‐human primate telemetry assays: Comparison of QTc interval prolongation by timepoint and concentration‐QTc analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_48aa2a376b114e3d9a08dccf46369978
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48aa2a376b114e3d9a08dccf46369978
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ISSN
1752-8054
E-ISSN
1752-8062
DOI
10.1111/cts.13103
