Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin
Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In the cerebellar cortex, Purkinje cells (PCs) receive signals from different inputs through their extensively branched dendrites and serve as an integration centre. Defects in the dendritic development of PCs thus disrupt cerebellar circuitry and cause ataxia. Here we report that specific inactivation of both
Lhx1
and
Lhx5
in postnatal...
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Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin
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TN_cdi_doaj_primary_oai_doaj_org_article_48c6986ca9f3427294ec05c869483932
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48c6986ca9f3427294ec05c869483932
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15079