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Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein a...

Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_498eebb319a240a9a5cd7fd3a54f3445

Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein as a potential treatment against human cancer

About this item

Full title

Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein as a potential treatment against human cancer

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-01, Vol.12 (1), p.1539-16, Article 1539

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Minichromosome Maintenance Complex Component 7 (MCM7) is a key component of the DNA replication licensing factor and hexamer MCM (MCM2–7) complex that regulates the DNA replication process. The MCM7 protein is associated with tumor cell proliferation that plays an important role in different human cancer progression. As the protein is highly expres...

Alternative Titles

Full title

Bioinformatics approaches identified dasatinib and bortezomib inhibit the activity of MCM7 protein as a potential treatment against human cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_498eebb319a240a9a5cd7fd3a54f3445

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_498eebb319a240a9a5cd7fd3a54f3445

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-05621-0

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