Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-genera...
Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Real-time quaking-induced conversion assay (RT-QuIC) exploits templating activity of pathogenic prion protein for ultrasensitive detection of prions. We have utilized second generation RT-QuIC assay to analyze matching
post-mortem
cerebrospinal fluid and skin samples of 38 prion disease patients and of 30 deceased neurological controls. The a...
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Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay
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TN_cdi_doaj_primary_oai_doaj_org_article_4a0a7a4517b84d01adcc462d7d759046
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a0a7a4517b84d01adcc462d7d759046
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-56789-6