MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing...
MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
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Oppermann, Johannes , Fischer, Paul , Silapetere, Arita , Liepe, Bernhard , Rodriguez-Rozada, Silvia , Flores-Uribe, José , Schiewer, Enrico , Keidel, Anke , Vierock, Johannes , Kaufmann, Joel , Broser, Matthias , Luck, Meike , Bartl, Franz , Hildebrandt, Peter , Wiegert, J. Simon , Béjà, Oded , Hegemann, Peter and Wietek, Jonas
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Channelrhodopsins (ChRs) are algal light-gated ion channels widely used as optogenetic tools for manipulating neuronal activity. ChRs desensitize under continuous bright-light illumination, resulting in a significant decline of photocurrents. Here we describe a metagenomically identified family of phylogenetically distinct anion-conducting ChRs (de...
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MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
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TN_cdi_doaj_primary_oai_doaj_org_article_4a9a09bdb29444b3a95997984a933cb5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a9a09bdb29444b3a95997984a933cb5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11322-6