Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization...
Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats
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Author / Creator
Fan, Hong , Tang, Hai-Bin , Shan, Le-Qun , Liu, Shi-Chang , Huang, Da-Geng , Chen, Xun , Chen, Zhe , Yang, Ming , Yin, Xin-Hua , Yang, Hao and Hao, Ding-Jun
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Oligodendrocytes (OLs) death after spinal cord injury (SCI) contributes to demyelination, even leading to a permanent neurological deficit. Besides apoptosis, our previous study demonstrated that OLs underwent receptor-interacting serine-threonine kinase 3(RIP3)/mixed lineage kinase domain-like protein (MLKL)-mediated necroptosis. Considering that...
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Full title
Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats
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TN_cdi_doaj_primary_oai_doaj_org_article_4b15e524bcbd4098b315836a88109b53
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b15e524bcbd4098b315836a88109b53
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-019-1613-2
