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Homogeneous and bioluminescent biochemical and cellular assay for monitoring cGAMP and enzymes that...

Homogeneous and bioluminescent biochemical and cellular assay for monitoring cGAMP and enzymes that...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b90b0813b674d84abdd79aca44d712c

Homogeneous and bioluminescent biochemical and cellular assay for monitoring cGAMP and enzymes that generate and degrade cGAMP

About this item

Full title

Homogeneous and bioluminescent biochemical and cellular assay for monitoring cGAMP and enzymes that generate and degrade cGAMP

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-12, Vol.14 (1), p.31165-11, Article 31165

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The cyclic GMP-AMP synthase-stimulator of the interferon gene (cGAS-STING) signaling pathway is considered an essential pattern recognition and effector pathway in the natural immune system and is mainly responsible for recognizing DNA molecules present in the cytoplasm and activating downstream signaling pathways to generate type I interferons (IF...

Alternative Titles

Full title

Homogeneous and bioluminescent biochemical and cellular assay for monitoring cGAMP and enzymes that generate and degrade cGAMP

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4b90b0813b674d84abdd79aca44d712c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b90b0813b674d84abdd79aca44d712c

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-82525-1

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