Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle...
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
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Author / Creator
Sliepen, Kwinten , Radić, Laura , Capella-Pujol, Joan , Watanabe, Yasunori , Zon, Ian , Chumbe, Ana , Lee, Wen-Hsin , de Gast, Marlon , Koopsen, Jelle , Koekkoek, Sylvie , del Moral-Sánchez, Iván , Brouwer, Philip J. M. , Ravichandran, Rashmi , Ozorowski, Gabriel , King, Neil P. , Ward, Andrew B. , van Gils, Marit J. , Crispin, Max , Schinkel, Janke and Sanders, Rogier W.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hepatitis C virus (HCV) infection affects approximately 58 million people and causes ~300,000 deaths yearly. The only target for HCV neutralizing antibodies is the highly sequence diverse E1E2 glycoprotein. Eliciting broadly neutralizing antibodies that recognize conserved cross-neutralizing epitopes is important for an effective HCV vaccine. Howev...
Alternative Titles
Full title
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
Authors, Artists and Contributors
Author / Creator
Radić, Laura
Capella-Pujol, Joan
Watanabe, Yasunori
Zon, Ian
Chumbe, Ana
Lee, Wen-Hsin
de Gast, Marlon
Koopsen, Jelle
Koekkoek, Sylvie
del Moral-Sánchez, Iván
Brouwer, Philip J. M.
Ravichandran, Rashmi
Ozorowski, Gabriel
King, Neil P.
Ward, Andrew B.
van Gils, Marit J.
Crispin, Max
Schinkel, Janke
Sanders, Rogier W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4bc99bb0318e4c848fb64b60030bf5d0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4bc99bb0318e4c848fb64b60030bf5d0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34961-8