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Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle...

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4bc99bb0318e4c848fb64b60030bf5d0

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate

About this item

Full title

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-11, Vol.13 (1), p.7271-16, Article 7271

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatitis C virus (HCV) infection affects approximately 58 million people and causes ~300,000 deaths yearly. The only target for HCV neutralizing antibodies is the highly sequence diverse E1E2 glycoprotein. Eliciting broadly neutralizing antibodies that recognize conserved cross-neutralizing epitopes is important for an effective HCV vaccine. Howev...

Alternative Titles

Full title

Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4bc99bb0318e4c848fb64b60030bf5d0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4bc99bb0318e4c848fb64b60030bf5d0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-34961-8

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