The NuRD complex cooperates with SALL4 to orchestrate reprogramming
The NuRD complex cooperates with SALL4 to orchestrate reprogramming
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Author / Creator
Wang, Bo , Li, Chen , Ming, Jin , Wu, Linlin , Fang, Shicai , Huang, Yi , Lin, Lihui , Liu, He , Kuang, Junqi , Zhao, Chengchen , Huang, Xingnan , Feng, Huijian , Guo, Jing , Yang, Xuejie , Guo, Liman , Zhang, Xiaofei , Chen, Jiekai , Liu, Jing , Zhu, Ping and Pei, Duanqing
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the early phase of somatic reprogramming. Sall4, Jdp2, Glis1 and Esrrb can reprogram MEFs to iPSCs efficiently, but only Sall4 is indispensable cap...
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Full title
The NuRD complex cooperates with SALL4 to orchestrate reprogramming
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4cb7569c25cc418daef3997fe87ba465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4cb7569c25cc418daef3997fe87ba465
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38543-0
